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Contact Details:

Physical Address             

Department of Dermatology,

Room 327, 3rd Floor

Nelson R Mandela School of Medicine

719 Umbilo Road

Congella

Durban

4013      


Postal Address

Department of Dermatology

Nelson R Mandela School of Medicine

Private Bag X 7

Congella

Durban

4013


Tel: + 27 31 3603546/ 2604531

Fax: + 27 31 3603549/ 2604531

Professor Anisa Mosam

Person

Professor Anisa Mosam

 

Telephone

(031) 260 4531

Email

Mosama@ukzn.ac.za

Campus

Nelson Mandela School of Medicine

Research Interests

HIV Skin disease

Designation

Associate Professor, Principal Specialist

Biosketch

Researchgate Profile

List of Publications

Mosam A, Uldrick TS, Shaik F, Carrara H, Aboobaker J, Coovadia HM.  Availability of highly active anti-retroviral therapy improves the ability to treat Kaposi’s sarcoma in South Africa.  .  Int J STD 2011; 22: 671-673. DOI: 10.1258/ijsa.2009.009145. 

Haddow LJ, Easterbrook PJ, Mosam A, Khanyile NG, Parboosing R, Moodley P, Moosa MYS. Defining Immune Reconstitution Inflammatory Syndrome: Evaluation of Expert Opinion versus two Case Definitions in a South African Cohort Clin Inf Dis 2009; 49:1424-1432 

Butler LM, Dorsey G, Hladik W, Rosenthal PJ, Brander C, Neilands T.B, Mbisa G, Whitby D, Kiepiela P, Mosam A, Mzolo S, Dollard S.C, Martin J.N. (2009) Kaposi's sarcoma-associated herpesvirus seroprevalence in population-based samples of African children: Evidence for at least two patterns of KSHV transmission. J Infect Dis. 2009 Aug 1; 200(3):430-438 

Mosam A, Aboobaker J, Shaik F. Kaposi’s sarcoma in sub-Saharan Africa: a current perspective. Curr Opin Infect Dis. 2010 Apr;23(2):119-23. Review 

Haddow LJ, Lehloenya R, Mosam A, Moosa MYS. Sweet syndrome: a novel manifestation of HIV-associated immune reconstitution inflammatory syndrome J Am Acad Dermatol. 2011 Jul;65(1):e23-5 

Dlova NC, Mosam A. Mycetoma. Skinmed. 2012 May-Jun;10(3):181. 

Recurrent giant molluscum contagiosum immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy in an HIV-infected South African Male. Drain P, Mosam A, D Gounder L, Gosnell B, Moosa Y. Int J STD AIDS. 2014 Mar 25(3):235-8 

Thandar Y, Botha J, Mosam A. Complementary Therapy in Atopic Eczema: The Latest Systematic Reviews. In press South Afr J Family Practice 

Lal K1, Dlova N, Mosam A, Khoza N. An infant presenting with multiple scalp ulcers 2014 Nov-Dec;31(6):729-30. doi: 10.1111/pde.12488. 

Katibi OS1, Dlova NC, Mosam A.  Cutaneous cytomegalovirus infection on multi dermatomal herpes zoster scars: an isotopic immune response 2015 Jan;40(1):42-4. doi: 10.1111/ced.12477. Epub 2014 Sep 30. 

Krown SE, Borok MZ, Campbell TB, Casper C, Dittmer DP, Hosseinipour MC, Mitsuyasu RT, Mosam A, Orem J, Phipps WT. Stage Stratified Approach to AIDS-related Kaposi’s Sarcoma: Implications for resource-limited environments. J Clin Oncol. 2014 Aug 10;32(23):2512-3. doi: 10.1200/JCO.2014.55.8999. Epub 2014 Jul 7. No abstract available. 

Totri C, Dlova CN, Mosam A, Khoza N. Oral Human Papillomavirus Lesions in an HIV-Positive Child. Consultant for Paediatrics CFP. 2015;14(4):186 

Stage-Stratified Approach to AIDS-Related Kaposi's Sarcoma: Implications for Resource-Limited Environments. Krown SE, Borok MZ, Campbell TB, Casper C, Dittmer DP, Hosseinipour MC, Mitsuyasu RT, Mosam A, Orem J, Phipps WT. J Clin Oncol. 2014 Jul 7. pii: JCO.2014.55.8999. PMID: 25002726 

HIV infection predisposes skin to toxic epidermal necrolysis via depletion of skin-directed CD4⁺ T cells. Yang C, Mosam A, Mankahla A, Dlova N, Saavedra A. J Am Acad Dermatol. 2014 Jun;70(6):1096-102. doi: 10.1016/j.jaad.2013.12.025. Epub 2014 Mar 12. PMID: 24629995 

Human T cell lymphotropic virus type 1- associated infective dermatitis in KwaZulu Natal, South Africa. Hlela C, Graham N, Bhigjee AI, Taylor GP, Khumalo NP, Mosam A. BMC Dermatol. 2013 Oct 23;13:11. doi: 10.1186/1471-5945-13-11. PMID: 24152710 

Recurrent giant molluscum contagiosum immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy in an HIV-infected man. Drain PK, Mosam A, Gounder L, Gosnell B, Manzini T, Moosa MY. Int J STD AIDS. 2014 Mar;25(3):235-8. doi: 10.1177/0956462413497702. Epub 2013 Jul 19. PMID: 23970647 

Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma: higher incidence and mortality in Africa than in the UK. Letang E, Lewis JJ, Bower M, Mosam A, Borok M, Campbell TB, Naniche D, Newsom-Davis T, Shaik F, Fiorillo S, Miro JM, Schellenberg D, Easterbrook PJ. AIDS. 2013 Jun 19;27(10):1603-13. doi: 10.1097/QAD.0b013e328360a5a1. PMID: 23462220 

Incidence, clinical spectrum, risk factors and impact of HIV-associated immune reconstitution inflammatory syndrome in South Africa. Haddow LJ, Moosa MY, Mosam A, Moodley P, Parboosing R, Easterbrook PJ. PLoS One. 2012;7(11):e40623. doi: 10.1371/journal.pone.0040623. Epub 2012 Nov 12. PMID: 23152745 

Mycetoma. Dlova NC, Mosam A. Skinmed. 2012 May-Jun;10(3):181. No abstract available. PMID: 22779102 

Actinomycetoma. Dlova NC, Mosam A. Skinmed. 2012 Mar-Apr;10(2):98. No abstract available. PMID:22545325 

Common skin conditions in children with HIV/AIDS. Mankahla A, Mosam A. Am J Clin Dermatol. 2012 Jun 1;13(3):153-66. doi: 10.2165/11593900-000000000-00000. Review. PMID: 22409242 

A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated Kaposi sarcoma in South Africa. Mosam A, Shaik F, Uldrick TS, Esterhuizen T, Friedland GH, Scadden DT, Aboobaker J, Coovadia HM. J Acquir Immune Defic Syndr. 2012 Jun 1;60(2):150-7. doi: 10.1097/QAI.0b013e318251aedd. PMID: 22395672 

An evaluation of the early effects of a combination antiretroviral therapy programme on the management of AIDS-associated Kaposi's sarcoma in KwaZulu-Natal, South Africa. Mosam A, Uldrick TS, Shaik F, Carrara H, Aboobaker J, Coovadia H. Int J STD AIDS. 2011 Nov;22(11):671-3. doi: 10.1258/ijsa.2009.009145. PMID: 22096054 

Sweet syndrome: adverse drug reaction or novel manifestation of HIV-associated immune reconstitution inflammatory syndrome? Haddow LJ, Lehloenya R, Mosam A, Malaka S, Moosa MY. J Am Acad Dermatol. 2011 Jul;65(1):e23-5. doi: 10.1016/j.jaad.2010.11.052. No abstract available. PMID: 21679803 

Quality of life in psoriasis patients in KwaZulu Natal, South Africa. Hariram P, Mosam A, Aboobaker J, Esterhuizen T. Indian J Dermatol Venereol Leprol. 2011 May-Jun;77(3):333-4. doi: 10.4103/0378-6323.79716. No abstract available. PMID: 21508577 

A population-based study of how children are exposed to saliva in KwaZulu-Natal Province, South Africa: implications for the spread of saliva-borne pathogens to children. Butler LM, Neilands TB, Mosam A, Mzolo S, Martin JN. Trop Med Int Health. 2010 Apr;15(4):442-53. doi: 10.1111/j.1365-3156.2010.02474.x. Epub 2010 Feb 9. PMID: 20149165  

Substantial regional differences in human herpesvirus 8 seroprevalence in sub-Saharan Africa: insights on the origin of the "Kaposi's sarcoma belt". Dollard SC, Butler LM, Jones AM, Mermin JH, Chidzonga M, Chipato T, Shiboski CH, Brander C, Mosam A, Kiepiela P, Hladik W, Martin JN.

Int J Cancer. 2010 Nov 15;127(10):2395-401. doi: 10.1002/ijc.25235. PMID: 20143397 

Kaposi's sarcoma in sub-Saharan Africa: a current perspective. Mosam A, Aboobaker J, Shaik F. Curr Opin Infect Dis. 2010 Apr;23(2):119-23. doi: 10.1097/QCO.0b013e328335b01a. Review. PMID: 19996745

Corticosteroid/cyclophosphamide pulse treatment in South African patients with pemphigus. Shaik F, Botha J, Aboobaker J, Mosam A. Clin Exp Dermatol. 2010 Apr;35(3):245-50. doi: 10.1111/j.1365-2230.2009.03450.x. Epub 2009 Oct 23. PMID: 19874327

RESEARCH GRANTS AWARDED

 

-          2002 University of Natal research Grant R 15 000

-          2003 Dermatology Association of South Africa Research Grant R40 000

-          2004 NRF Thuthuka Grant “Women in Research” R 121 000 AIDS Kaposi’s sarcoma

-          2004 AIDS Malignancy Consortium Grant $ 36 000

-          2004 Building capacity for KSHV research in Sub-Saharan Africa $10 000

-          2005 Doris Duke ACRiA grant for AIDS Research in Africa $ 64 000 “Management of HIV Kaposi’s sarcoma in resource poor settings

-          2005 NRF Thuthuka Grant “Women in Research 129 000 AIDS Kaposi’s sarcoma

-          2005 MRC Research Development Grant “Dermatophytosis in HIV/AIDS” R 50 000

-          2006 NRF Thuthuka Grant R 60 000 AIDS Kaposi’s Sarcoma

-          2007 NRF Thuthuka Grant  R 90 000 AIDS Kaposi’s sarcoma

-          2008 NRF Thuthuka Grant  R 90 000  AIDS Kaposi’s sarcoma

-          2009- 2013 Developmental Grant for Rated Researchers R 40 000

-          1D43CA153715-01, 08/27/2010 – 07/31/2013   $ 1 577 568

-          Columbia-South Africa Training Program for Research on HIV-associated Malignancies

This is an NIH Training Grant for development of individuals in clinical, epidemiological, virological or immunological aspects related to malignancies in HIUV/AIDS: Kaposi’s sarcoma, Lymphoma and Ca cervix.

The partner institution in the US in Columbia University with 3 South African based universities participating: UKZN, University of Witwatersrand and Stellenbosch. I am the South Africa PI on this grant

Role: South Africa PI

 

-          NRF Incentive Funding for rated Researchers     1/04/2010- 31/12/2010  R40 000

-          3D43TW000231-14S1 01/05/08-30/04/2010

 

Building capacity for patient oriented research in HIV-associated Kaposi sarcoma in Kwazulu-Natal, South Africa

This grant was in a collaborative venture with the Fogarty training programme between CAPRISA and Columbia university headed by Prof Abdool Karrim. It enabled training of research fellows in laboratory procedures, clinical management as well as epidemiology of Kaposi’s Sarcoma

 

SUPERVISION OF RESEARCH

 

-          Co supervisor of Ms U Bodasings MSc thesis “Adherence to Highly Active Antiretroviral Therapy (HAART) for the Management of Kaposis’s Sarcoma in sub-Saharan Africa (graduated 2006)

-          Supervisor of Dr C Hlela’s MMed Thesis “HTLV Dermatoses in KwaZulu Natal, South Africa” graduated 2008.  Graduated 2008

-          *Supervisor of MMEd Sci K Hoosen “ An Assessment of the Quality of Life of patients with HIV Kaposi’s sarcoma treated with HAART” graduated 2007

-          *Supervisor of O El Koha’s MMed (Oncology) thesis “Prognostic factors predicting response to chemotherapy in patients with HIV Kaposi’s sarcoma”. (graduated 2006)

-          *Supervisor of Dr P Harirams MMed thesis “Quality of Life of patients with Psoriasis” project complete, manuscript accepted IJDVL 2011 May-Jun;77(3):333-4.Student graduated in 2013

-          *Supervisor of Ms S Singhs MMed Sci Thesis “ Seroprevalence and Viral Quantification of KSHV in an HIV Positive South African Adult cohort” Accepted by postgraduate and ethics committees

-          Supervisor of  S Nkwanyanas MMed in Somatology “An exploration of the relationship between somatolgists/aestheticians and medical professionals practising non-invasive aesthetics and anti aging medicine in the Ethekwini area of Kwazulu Natal, South Africa DUT write up in progress

-          Supervisor of Dr L Naidoo’s MMed “ Characteristics of Patients with HIV KS in the HAART era”

-          Supervisor of Dr Yorks MMed Sci “Primary Cutaneous Malignancies in the Northern Cape Province of South Africa: A Histopathological Review.” Ethical and postgrad approval obtained 2013

-          Supervisor of Dr Chateaus MMed Sci “The outcome of HIV positive patients with SJS./TEN treated with steroids”

-          Supervisor of PhD for P Hariram “HPV detection and genotyping of cutaneous warts in HIV patients” Concept Sheet approved

-          Co-supervisor of Y Thandars PhD “AN INVESTIGATION INTO THE USE OF COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM) IN PAEDIATRIC PATIENTS WITH ATOPIC ECZEMA IN DURBAN, KWAZULU-NATAL – A PROSPECTIVE, OBSERVATIONAL COHORT STUDY

 


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